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. 2024 Jul 29;19(1):20220922. doi: 10.1515/biol-2022-0922

Figure 5.

Figure 5

Met inhibits the PI3K/AKT/mTOR signaling pathway activation. (a) Immunohistochemistry of p-PI3K, PI3K, p-AKT, AKT, p-mTOR, and mTOR expression. Scale bar = 50 μm. (b) Quantitative analysis of p-PI3K/PI3K, p-AKT/AKT, and p-mTOR/mTOR immunohistochemistry. (c) Western blot analysis of PI3K, p-PI3K, AKT, p-AKT, mTOR, and p-mTOR in cartilage tissue. (d) Quantitative data of PI3K, p-PI3K, AKT, p-AKT, mTOR, and p-mTOR western blot analysis. Data are presented as mean ± SD (n = 3). ns, no significance; *P < 0.05; **P < 0.01; ***P < 0.001.