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. 2023 Oct 31;63(8):2222–2229. doi: 10.1093/rheumatology/kead574

Table 2.

Outcomes during hospitalizations for gout flares, comparing the pre- and post-implementation cohorts

Outcome Pre-implementation, n (%) (n = 119) Post-implementation, n (%) (n = 108) Odds ratio (95% CI) P-value
Rheumatology input during hospitalization 65 (54.6) 82 (75.9) 2.48 (1.37, 4.52) 0.003
Serum urate level performed 79 (66.4) 100 (92.6) 6.32 (2.75, 14.5) <0.001
Joint aspiration performed 23 (19.3) 51 (47.2) 3.44 (1.88, 6.27) <0.001
Flare treatment prescribed 111 (93.3) 106 (98.1) 4.46 (0.91, 21.8) 0.065
 NSAIDs 38 (31.9) 34 (31.5) 1.18 (0.61, 2.28) 0.63
 Colchicine 74 (62.2) 86 (79.6) 2.30 (1.23, 4.31) 0.009
 Corticosteroids 25 (21.0) 40 (37.0) 2.20 (1.21, 4.02) 0.010
 Multiple flare treatments prescribed 21 (17.6) 49 (45.4) 4.10 (2.20, 7.67) <0.001
 Intra-articular steroid injection 2 (1.7) 9 (8.3) 5.53 (1.15, 26.7) 0.033
Disease education documented prior to discharge 27 (22.7) 24 (22.2) 1.00 (0.53, 1.90) 0.99
ULT initiated and/or titrated during hospitalization 21 (17.6) 67 (62.0) 7.69 (4.12, 14.4) <0.001
Gout recommendations documented on discharge 70 (58.8) 93 (86.1) 4.33 (2.21, 8.48) <0.001
 Recommendation to initiate and/or titrate ULT after discharge 18 (15.1) 42 (38.9) 3.26 (1.71, 6.19) <0.001
 Recommendation for prophylaxis while titrating ULT 23 (19.3) 13 (12.0) 0.54 (0.26, 1.15) 0.11
 Recommendation for target serum urate level 13 (10.9) 28 (25.9) 2.56 (1.23, 5.36) 0.012
 Recommendation for primary care follow-up 53 (44.5) 43 (39.8) 0.82 (0.48, 1.41) 0.47
 Recommendation for rheumatology/gout clinic follow-up 11 (9.2) 73 (67.6) 19.8 (9.34, 42.0) <0.001

Odds ratios from logistic regression models are shown, with adjustment for age and sex. ULT: urate-lowering therapy.