TABLE 3.
Multivariable Logistic Regression Model: Preoperative and Intraoperative Characteristics C-statistic: 0.604
| Patient Characteristics | Adjusted OR | 95% CI | P |
|---|---|---|---|
|
| |||
| Preoperative characteristics | |||
| Age (per 10-y increase) | 1.09 | (1.04–1.15) | 0.0003 |
| Male | 1.18 | (1.09–1.28) | <0.0001 |
| Race (reference: white) | |||
| Black | 1.04 | (0.91–1.18) | 0.6 |
| Asian | 0.63 | (0.47–0.83) | 0.001 |
| Hispanic | 1.01 | (0.76–1.34) | 0.9 |
| Other | 1.04 | (0.77–1.41) | 0.8 |
| Insurance status (reference: medicare/other) | |||
| Medicaid | 1.22 | (1.02–1.45) | 0.03 |
| None/self-pay | 1.01 | (0.74–1.38) | 0.9 |
| Clinical Stage (reference: Stage I) | |||
| Stage II | 1.12 | (1.01–1.24) | 0.03 |
| Stage III | 1.06 | (0.91– 1.23) | 0.5 |
| Stage IV | 1.26 | (0.94–1.70) | 0.1 |
| BMI | 0.99 | (0.98–0.99) | 0.0002 |
| FEV1% ≤80% predicted | 0.90 | (0.86–0.94) | <0.0001 |
| FEV1% >80% predicted | 0.98 | (0.95–1.02) | 0.4 |
| Cigarette smoking (reference: never smoker) | |||
| Former smoker | 1.10 | (0.96–1.25) | 0.2 |
| Current smoker | 1.22 | (1.05–1.41) | 0.009 |
| Interstitial fibrosis | 1.66 | (1.28–2.14) | 0.0001 |
| Hypertension | 0.98 | (0.90–1.07) | 0.6 |
| Steroids | 1.43 | (1.19–1.73) | 0.0002 |
| Congestive heart failure | 1.01 | (0.78–1.31) | 0.9 |
| Coronary artery disease | 1.14 | (1.03–1.27) | 0.01 |
| Peripheral vascular disease | 1.21 | (1.06–1.37) | 0.004 |
| Cerebrovascular disease | |||
| Transient ischemic attack | 1.10 | (0.92–1.31) | 0.3 |
| Cerebrovascular accident | 1.38 | (1.15–1.66) | 0.0007 |
| Diabetes | 1.08 | (0.98–1.19) | 0.1 |
| Induction chemotherapy alone | 0.82 | (0.63–1.07) | 0.1 |
| Induction chemoradiation therapy | 1.31 | (0.95–1.80) | 0.1 |
| Creatinine ≥2 | 1.10 | (0.80–1.51) | 0.5 |
| Preoperative dialysis | 1.24 | (0.73–2.10) | 0.4 |
| Zubrod score (reference: 0) | |||
| 1 | 1.14 | (1.04–1.24) | 0.003 |
| 2 or 3 | 1.32 | (1.10–1.57) | 0.003 |
| ASA class (reference: I or II) | |||
| III | 1.19 | (1.06–1.35) | 0.005 |
| Intraoperative characteristics | |||
| Open (reference: minimally invasive) | 1.17 | (1.07–1.27) | 0.0007 |
| Reoperation | 1.01 | (0.88–1.15) | 0.9 |
| Lobe (reference: upper lobe) | |||
| Middle lobe | 0.75 | (0.64–0.89) | 0.001 |
| Lower lobe | 1.15 | (1.05–1.25) | 0.002 |
| Unspecified* | 1.28 | (0.93–1.77) | 0.1 |
| Intraoperative PRBCs | 1.31 | (1.01–1.69) | 0.04 |
| IV antibiotics given within 1 h of incision | 0.86 | (0.64–1.16) | 0.3 |
| DVT prophylaxis | 0.96 | (0.54–1.71) | 0.9 |
| Cephalosporin antibiotic ordered | 0.96 | (0.75–1.24) | 0.8 |
ICU indicates intensive care unit; IV, intravenous; PRBC, packed red blood cells.
*
Missing data for n = 574 patients (1.4%).