Skip to main content
. 2024 Aug 1;22(8):e8897. doi: 10.2903/j.efsa.2024.8897
OECD QSAR toolbox VEGA
Aleuritic acid

No alert

(H‐acceptor‐path‐3‐H‐acceptor)

Ames test: non‐mutagenic (consensus 0.9), inactive in in vitro chromosomal aberrations, in vitro and in vivo micronucleus
Jalaric acid

DNA binding by OECD: Schiff base former

In vitro and in vivo mutagenicity by ISS: simple aldehyde

Ames test: mutagenic (Consensus score: 0.2); Micronucleus: active in vitro, inactive in vivo
Laccijalaric acid

DNA binding by OECD: Schiff base former

In vitro and in vivo mutagenicity by ISS: simple aldehyde

Ames test: mutagenic (Consensus score: 0.45); Micronucleus: active in vitro, inactive in vivo
Laccilaksholic acid No alert Ames test: non‐mutagenic (Consensus score: 0.25); Micronucleus: active in vitro, inactive in vivo
Shelloic acid No alert Ames test: non‐mutagenic (Consensus score: 0.25); Micronucleus: active in vitro, inactive in vivo
Jalaric aleuratitate/shellac monomer

DNA binding by OECD: Schiff base former

In vitro and in vivo mutagenicity by ISS: simple aldehyde

(H‐acceptor‐path‐3‐H‐acceptor)

Ames test: non‐mutagenic (Consensus score: 0.525); Micronucleus: active in vitro, inactive in vivo
Laksholic acid No alert Ames test: non‐mutagenic (Consensus score: 0.45); Micronucleus: active in vitro, inactive in vivo
Butolic acid No alert Ames test: non‐mutagenic (Consensus score: 0.9); Micronucleus: active in vitro, inactive in vivo