| OECD QSAR toolbox | VEGA | |
|---|---|---|
| Aleuritic acid |
No alert (H‐acceptor‐path‐3‐H‐acceptor) |
Ames test: non‐mutagenic (consensus 0.9), inactive in in vitro chromosomal aberrations, in vitro and in vivo micronucleus |
| Jalaric acid |
DNA binding by OECD: Schiff base former In vitro and in vivo mutagenicity by ISS: simple aldehyde |
Ames test: mutagenic (Consensus score: 0.2); Micronucleus: active in vitro, inactive in vivo |
| Laccijalaric acid |
DNA binding by OECD: Schiff base former In vitro and in vivo mutagenicity by ISS: simple aldehyde |
Ames test: mutagenic (Consensus score: 0.45); Micronucleus: active in vitro, inactive in vivo |
| Laccilaksholic acid | No alert | Ames test: non‐mutagenic (Consensus score: 0.25); Micronucleus: active in vitro, inactive in vivo |
| Shelloic acid | No alert | Ames test: non‐mutagenic (Consensus score: 0.25); Micronucleus: active in vitro, inactive in vivo |
| Jalaric aleuratitate/shellac monomer |
DNA binding by OECD: Schiff base former In vitro and in vivo mutagenicity by ISS: simple aldehyde (H‐acceptor‐path‐3‐H‐acceptor) |
Ames test: non‐mutagenic (Consensus score: 0.525); Micronucleus: active in vitro, inactive in vivo |
| Laksholic acid | No alert | Ames test: non‐mutagenic (Consensus score: 0.45); Micronucleus: active in vitro, inactive in vivo |
| Butolic acid | No alert | Ames test: non‐mutagenic (Consensus score: 0.9); Micronucleus: active in vitro, inactive in vivo |