OECD QSAR toolbox | VEGA | |
---|---|---|
Aleuritic acid |
No alert (H‐acceptor‐path‐3‐H‐acceptor) |
Ames test: non‐mutagenic (consensus 0.9), inactive in in vitro chromosomal aberrations, in vitro and in vivo micronucleus |
Jalaric acid |
DNA binding by OECD: Schiff base former In vitro and in vivo mutagenicity by ISS: simple aldehyde |
Ames test: mutagenic (Consensus score: 0.2); Micronucleus: active in vitro, inactive in vivo |
Laccijalaric acid |
DNA binding by OECD: Schiff base former In vitro and in vivo mutagenicity by ISS: simple aldehyde |
Ames test: mutagenic (Consensus score: 0.45); Micronucleus: active in vitro, inactive in vivo |
Laccilaksholic acid | No alert | Ames test: non‐mutagenic (Consensus score: 0.25); Micronucleus: active in vitro, inactive in vivo |
Shelloic acid | No alert | Ames test: non‐mutagenic (Consensus score: 0.25); Micronucleus: active in vitro, inactive in vivo |
Jalaric aleuratitate/shellac monomer |
DNA binding by OECD: Schiff base former In vitro and in vivo mutagenicity by ISS: simple aldehyde (H‐acceptor‐path‐3‐H‐acceptor) |
Ames test: non‐mutagenic (Consensus score: 0.525); Micronucleus: active in vitro, inactive in vivo |
Laksholic acid | No alert | Ames test: non‐mutagenic (Consensus score: 0.45); Micronucleus: active in vitro, inactive in vivo |
Butolic acid | No alert | Ames test: non‐mutagenic (Consensus score: 0.9); Micronucleus: active in vitro, inactive in vivo |