Table 2:
Annual change in estimated glomerular filtration rate before and after dapagliflozin administration and initial dip in estimated glomerular filtration rate after introduction of dapagliflozin.
Patient | eGFR (ml/min/1.73 m2) | Pre-eGFR slope (ml/min/1.73 m2/year) | Post-eGFR slope (ml/min/1.73 m2/year) | ΔeGFR slope (ml/min/1.73 m2/year) | Initial dip in eGFR (%) |
---|---|---|---|---|---|
1 | 22.6 | −1.1 | −2.3 | −1.2 | 22.7 |
2 | 21.8 | −1.9 | −0.6 | 1.3 | 12.2 |
3 | 26.9 | NA | −0.1 | NA | 12.9 |
4 | 44.8 | −2.6 | −0.8 | 1.8 | 19.6 |
5 | 38.5 | −3.3 | −1.9 | 1.4 | 0 |
6 | 43.1 | −3.0 | −1.9 | 1.1 | 0 |
7 | 23.3 | −2.9 | −2.8 | 0.1 | 4.9 |
pre-eGFR slope, annual change in eGFR before dapagliflozin initiation; post-eGFR slope, annual change in eGFR after dapagliflozin initiation; ΔeGFR slope, post-eGFR slope − pre-eGFR slope