FIG. 1.

Clinical and laboratory strains of HSV-1 and HSV-2 inhibit UV-induced apoptosis. Jurkat cells were mock or HSV infected for 5 h prior to induction of apoptosis with UV radiation. The morphological changes of apoptosis were assessed by a blinded observer using fluorescence microscopy. (A) Uninfected cells without UV irradiation; (B) uninfected cells after UV irradiation; (C) HSV-1-infected cells (strain H61146) after treatment with UV; (D and E) percent apoptosis after infection with a clinical (F28700, F43031, and T75419) or laboratory (E115 and 333) strains of HSV-1 (D) and HSV-2 (E). Shown is mean + SEM of two to five independent experiments. In some instances, error bars are too small to be seen.