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| time (h) | open system (%) | closed system (%) |
|---|---|---|
| 0 | 100 ± 0.0 | 100 ± 0.0 |
| 1 | 97.6 ± 0.0 | 95.3 ± 0.1 |
| 2 | 98.0 ± 0.1 | 95.0 ± 0.2 |
| 4 | 100.3 ± 0.5 | 104.6 ± 0.2 |
| 6 | 103.9 ± 0.1 | 97.9 ± 0.1 |
| 24 | 113.5 ± 0.1 | 110.8 ± 0.2 |
| 48 | 114.3 ± 0.0 | 124.1 ± 0.1 |
