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. 2024 Jul 31;17:11786469241266312. doi: 10.1177/11786469241266312

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© The Author(s) 2024

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 1. — Measured tryptophan concentration on the apical and basolateral side upon treatment for 2, 6 and 21 hours with 0 μM (A), 1 μM (B₁), 3 μM (C₁) and 10 μM (D₁) tryptophan. Results shown as mean ± SD of 3 to 4 independent experiments (N = 6-9). X-fold values referred to the applied stock solution upon subtraction of measured tryptophan concentration after treatment with 0 μM (A) for each timepoint shown for 1 μM (B₂), 3 μM (C₂) and 10 μM (D₂). Results shown as mean ± SD. Statistical analysis was performed as two-way ANOVA using post-hoc Holm-Sidak test with *P < .05, **P < .01, ***P < .001 and α = .05 comparing measured apical concentration to measured basolateral concentration for each respective Trp concentration applied.