Table 3.
CMR Characteristics of Study Participants
| Variables | Summary statistics | P values (Holm adj.) | ||||
|---|---|---|---|---|---|---|
| Control, N=20* | HFpEF, N=33* | HFrEF, N=28* | Control vs HFpEF | Control vs HFrEF | HFpEF vs HFrEF | |
| LV mass index, g/m2 | 44 (8) | 62 (22) | 87 (44) | 0.05 | <0.01 | <0.01 |
| LVEDV index, mL/m2 | 68 (11) | 73 (29) | 151 (81) | 0.75 | <0.01 | <0.01 |
| LVESV index, mL/m2 | 24 (5) | 30 (19) | 112 (74) | 0.61 | <0.01 | <0.01 |
| LVSV index, mL/m2 | 44 (8) | 42 (4) | 40 (9) | 0.58 | 0.18 | 0.57 |
| LVEF, % | 65 (5) | 60 (10) | 30 (9) | 0.03 | <0.01 | <0.01 |
| LAVI, mL/m2 | 25 (8) | 36 (17) | 39 (20) | 0.06 | 0.02 | 0.48 |
| LV/RV mass ratio | 0.67 (0.12) | 0.93 (0.34) | 0.60 (0.16) | <0.01 | 0.36 | <0.01 |
| RV mass index, g/m2 | 15 (4) | 14 (5) | 17 (4) | 0.15 | 0.10 | 0.12 |
| RVEDV index, mL/m2 | 70 (11) | 60 (2) | 68 (25) | <0.01 | 0.29 | 0.18 |
| RVESV index, mL/m2 | 33 (5) | 30 (1) | 38 (20) | 0.07 | 0.34 | 0.08 |
| RVSV index, mL/m2 | 40 (6) | 30 (9) | 30 (8) | 0.01 | 0.50 | 0.08 |
| RVEF, % | 53 (2) | 49 (9) | 45 (10) | 0.03 | <0.01 | 0.14 |
| Native T2, ms | 53 (9) | 56 (8) | 58 (9) | 0.58 | 0.32 | 0.58 |
| Native T1, ms | 1210 (84) | 1259 (67) | 1269 (71) | 0.05 | 0.03 | 0.62 |
| ECV, % | 0.276 (0.04) | 0.319 (0.06) | 0.309 (0.05) | 0.01 | 0.06 | 0.48 |
| ECV (no LGE), % | 0.276 (0.04) | 0.317 (0.05) | 0.306 (0.04) | <0.01 | 0.02 | 0.43 |
| LV cardiomyocyte mass, g/m2 (IQR) | 32 (28, 37) | 41 (31, 48) | 53 (42, 78) | 0.02 | <0.01 | 0.01 |
| Presence of LGE | 0 (0) | 16 (50) | 19 (70) | <0.01 | <0.01 | 0.19 |
| LGE typical for coronary artery disease | 0 (0, 0) | 4 (11.8) | 1 (3.6) | <0.01 | <0.01 | 0.27 |
| LGE mass, g/m2 | 0 | 10.5 (6, 16) | 10.7 (6, 21) | <0.01 | <0.01 | 0.91 |
ECV indicates extracellular volume; HFpEF, heart failure with preserved ejection fraction; HFrEF, heart failure with reduced ejection fraction; IQR, interquartile range; LAVI, left atrial volume index; LGE, late gadolinium enhancement; LV, left ventricular; LVEDV, left ventricular end‐diastolic volume; LVEF, left ventricular ejection fraction; LVESV, left ventricular end‐systolic volume; LVSV, left ventricular stroke volume; RV, right ventricular; RVEDV, right ventricular end‐diastolic volume; RVEF, right ventricular ejection fraction; RVESV, right ventricular end‐systolic volume; RVSV, right ventricular stroke volume.
*
n (%); median (IQR); mean (SD).