Table 3.
Difference in 3‐Month Poststroke Outcomes Associated With an IQR Difference in Density of Resources
| Model* | ADL/IADL (N=1284) | 3MSE (N=1284) | ||
|---|---|---|---|---|
| IQR difference (95% CI) | P value | IQR difference (95% CI) | P value | |
| 1: Unadjusted | 0.051 (−0.035 to 0.138) | 0.2441 | 0.343 (−0.841 to 1.526) | 0.5703 |
| 2: 1+Demographics | 0.042 (−0.033 to 0.117) | 0.2734 | 0.319 (−0.665 to 1.304) | 0.5250 |
| 3: 2+Individual SES | 0.043 (−0.029 to 0.114) | 0.2419 | 0.279 (−0.498 to 1.055) | 0.4819 |
| 4: 3+Prestroke health and behaviors | 0.021 (−0.042 to 0.084) | 0.5185 | 0.549 (−0.201 to 1.300) | 0.1514 |
| 5: 4+Interpersonal factors | 0.016 (−0.046 to 0.078) | 0.6156 | 0.608 (0.376 to −0.130) | 0.1065 |
| 6: 5+Neighborhood SES | −0.008 (−0.068 to 0.053) | 0.8077 | 0.776 (0.030 to 1.522) | 0.0415 |
| 7: 6+Stroke type and severity | −0.015 (−0.075 to 0.045) | 0.6207 | 0.838 (0.092 to 1.584) | 0.0277 |
|
8: 7+Stroke severity interaction Mild Moderate–severe |
0.020 (−0.046 to 0.086) ‡ −0.156 (−0.284 to −0.027) ‡ |
0.0145 † 0.5502 0.0176 |
0.613 (−0.216 to 1.443) ‡ 1.714 (−0.004 to 3.433) ‡ |
0.2591 † 0.1474 0.0506 |
|
9: 7+Sex interaction Male Female |
0.019 (−0.061 to 0.098) −0.054 (−0.139 to 0.031) |
0.2036 † 0.6407 0.2154 |
1.217 (0.187 to 2.247) ‡ 0.411 (−0.684 to 1.506) ‡ |
0.2963 † 0.0206 0.4615 |
|
10: 7+Race and ethnicity interaction Mexican American Non‐Hispanic White |
0.003 (−0.074 to 0.081) ‡ −0.041 (−0.131 to 0.049) ‡ |
0.4540 † 0.9321 0.3753 |
1.167 (0.194 to 2.140) ‡ 0.381 (−0.789 to 1.551) |
0.3145 † 0.0188 0.5232 |
| SS‐QoL (N=1189) | PHQ‐8 (N=1086) | |||
|---|---|---|---|---|
| 1: Unadjusted | −0.016 (−0.123 to 0.092) | 0.7759 | 0.114 (−0.529 to 0.757) | 0.7281 |
| 2: 1+Demographics | −0.007 (−0.098 to 0.085) | 0.8861 | 0.097 (−0.440 to 0.634) | 0.7232 |
| 3: 2+Individual SES | −0.003 (−0.088 to 0.081) | 0.9372 | 0.098 (−0.418 to 0.614) | 0.7100 |
| 4: 3+Prestroke health and behaviors | 0.028 (−0.043 to 0.100) | 0.4410 | −0.036 (−0.529 to 0.457) | 0.8854 |
| 5: 4+Interpersonal factors | 0.029 (−0.042 to 0.100) | 0.4187 | −0.033 (−0.529 to 0.463) | 0.8962 |
| 6: 5+Neighborhood SES | 0.051 (−0.019 to 0.121) | 0.1502 | −0.065 (−0.549 to 0.419) | 0.7915 |
| 7: 6+Stroke type and severity | 0.058 (−0.010 to 0.125) | 0.0933 | −0.083 (−0.569 to 0.404) | 0.7385 |
|
8: 7+Stroke severity interaction Mild Moderate–severe |
0.025 (−0.051 to 0.102) 0.194 (0.029 to 0.359) |
0.0779 † 0.5186 0.0214 |
−0.034 (−0.581 to 0.514) −0.294 (−1.461 to 0.872) |
0.6966 † 0.9042 0.6207 |
|
9: 7+Sex interaction Male Female |
0.074 (−0.022 to 0.170) 0.039 (−0.067 to 0.145) |
0.6459 † 0.1293 0.4689 |
−0.420 (−1.093 to 0.253) −0.317 (−0.420 to 1.054) |
0.1583 † 0.2215 0.3990 |
|
10: 7+Race and ethnicity interaction Mexican American Non‐Hispanic White |
0.060 (−0.061 to 0.151) 0.054 (−0.053 to 0.161) |
0.9322 † 0.1941 0.3206 |
0.013 (−0.646 to 0.672) −0.205 (−0.959 to 0.549) |
0.6761 † 0.9701 0.5935 |
3MSE indicates Modified Mini‐Mental State Exam; ADL/IADL, activities of daily living/instrumental activities of daily living; HR, hazard ratio; IQR, interquartile range; PHQ‐8, Patient Health Questionnaire 8; SES, socioeconomic status; and SS‐QoL, abbreviated Stroke‐Specific Quality of Life scale.
(1) Unadjusted model sequentially adjusted for (2) age quartile, sex, race and ethnicity; (3) education attainment, insurance; (4) modified Rankin scale, informant questionnaire on cognitive decline in the elderly, depression, comorbidity score, smoking; (5) marital status, social support score; (6) neighborhood disadvantage score, neighborhood affluence score; (7) stroke type and severity. Interactions terms applied to model 7 for (8) stroke severity, (9) sex, and (10) race and ethnicity.
Interaction term P value.
HRs computed for each stratum of interaction term using coefficients for resource density and interaction terms.