Table 2.
Association of Remnant Cholesterol Levels at Admission With Risk of Bleeding and Death
| Model 1 | Model 2 | Risk difference (95% CI), % | ||||||
|---|---|---|---|---|---|---|---|---|
| OR | 95% CI | P value | OR | 95% CI | P value | Model 1 | Model 2 | |
| Bleeding event | ||||||||
| Continuous, mg/dL | 0.979 | 0.958–0.997 | 0.034 | 0.980 | 0.960–0.998 | 0.048 | … | … |
| 20–29.9 mg/dL | Reference | |||||||
| <20 mg/dL | 1.891 | 1.130–3.344 | 0.021 | 2.564 | 1.121–6.668 | 0.036 | 1.7 (0.4 to 3.0) | 2.5 (0.5 to 4.4) |
| ≥30 mg/dL | 1.272 | 0.612–2.603 | 0.511 | 1.170 | 0.338–3.769 | 0.794 | 0.5 (−1.1 to 2.2) | 0.3 (−1.8 to 2.4) |
| Death in hospital | ||||||||
| Continuous, mg/dL | ||||||||
| 20–29.9 mg/dL | 0.987 | 0.962–1.007 | 0.275 | 0.999 | 0.976–1.017 | 0.935 | … | … |
| <20 mg/dL | 1.293 | 0.687–2.612 | 0.446 | 1.763 | 0.516–7.368 | 0.393 | 0.4 (−0.6 to 1.5) | 1.0 (−1.1 to 3.1) |
| ≥30 mg/dL | 1.051 | 0.387–2.651 | 0.917 | 0.868 | 0.042–6.906 | 0.905 | 0.1 (−1.4 to 1.5) | −0.2 (−3.3 to 2.9) |
Model 1 was adjusted for age and sex; model 2 was further adjusted for BMI, smoking, hypertension, diabetes, myocardial infarction, atrial fibrillation, prior stroke, eGFR, TOAST subtype, lipid‐lowering treatment before admission, intravenous thrombolytic therapy and mechanical thrombectomy, LDL cholesterol and HDL cholesterol. BMI indicates body mass index; eGFR, estimated glomerular filtration rate; HDL, high‐density lipoprotein; LDL, low‐density lipoprotein; OR, odds ratio; and TOAST, Trial of ORG 10172 in Acute Stroke Treatment.