Title {1}	The effect of astaxanthin supplementation on inflammatory markers, oxidative stress indices, lipid profile, uric acid level, blood pressure, endothelial function, quality of life, and disease symptoms in heart failure subjects
Trial registration {2a and 2b}.	IRCT20200429047235N3; 26 March 2024.
Protocol version {3}	Version 1, April 2024.
Funding {4}	Isfahan university of medical sciences. Grant number:3402807
Author details {5a}	Shirin Ghotboddin Mohammadi1, Awat Feizi2, Mohammad Bagherniya3, Davood Shafie4, Ali-Reza Ahmadi5, Marziyeh kafeshani6 1Department of Clinical Nutrition, School of Nutrition & Food Sciences, Isfahan University of Medical Sciences, Isfahan, Iran. 2Epidemiology and Biostatistics Department, Health School, Isfahan University of Medical Sciences, Isfahan, Iran 3Department of Community Nutrition, Food Security Research Center, School of Nutrition and Food Science Isfahan University of Medical Sciences Isfahan Iran. 4Heart Failure Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran. 5Department of Biomedical Sciences, Women Research Center, Alzahra University, Tehran, Iran 6Nutrition and Food Security Research Center and Department of Clinical Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran
Name and contact information for the trial sponsor {5b}	Isfahan University of Medical Sciences Postal Code: 81,746–73,461 Tell: (+ 98)-31–3668–0048
Role of sponsor {5c}	Financial support and supervision