Figure 2.

Postoperative changes in neuropsychological performance. (A) Longitudinal trajectories in FSIQ in seizure-free (green) versus not seizure-free (orange) patients. Only patients with two or more postoperative assessments were included. All postoperative assessments were included for each patient. Linear modelling was fitted to all data-points, according to seizure outcome (dashed green line for patients who were seizure free and dashed orange line for patients who were not seizure free); shaded areas represent the 95% confidence intervals. (B) Individual change in postoperative FSIQ in seizure-free (green) versus not seizure-free (orange) patients. The distribution of change scores is represented using a density plot. The change score for each patient was computed by subtracting the first postoperative score for the patient from their last postoperative score. The median change scores are displayed with a green dashed line (in seizure-free patients) and with an orange dashed line (in not seizure-free patients). Only patients with two or more postoperative assessments were included in the visualization. See Supplementary Fig. 3 for verbal IQ, performance IQ, working memory, processing speed, reading, spelling and numeracy. FSIQ = full-scale IQ.