Table 4.
Distribution of family history findings and ages at onset among the ROPAD study participants and patients with a positive Parkinson’s disease-relevant genetic test
| All ROPAD study participants | Patients with a positive PDGT | ROPAD study participants with positive family history | Patients with positive family history and a positive PDGT | |||||
|---|---|---|---|---|---|---|---|---|
| AAO (years) | n (%) | n (%) | ROPAD participants of the respective AAO range (%) | n (%) | n (%) | Percentage of the ROPAD study participants | Percentage of the ROPAD study participants with positive family history | Percentage of all individuals with a positive PDGT |
| ≤20 | 73 (0.6) | 27 (1.4) | 37.0 | 31 (0.9) | 15 (2.3) | 20.5 | 48.4 | 0.8 |
| ≤30 | 261 (2.1) | 79 (4.2) | 30.3 | 100 (2.9) | 39 (5.9) | 14.9 | 39.0 | 2.1 |
| ≤40 | 1145 (9.1) | 269 (14.4) | 23.5 | 367 (10.8) | 119 (18.0) | 10.4 | 32.4 | 6.4 |
| ≤50 | 3445 (27.4) | 684 (36.7) | 19.9 | 1033 (30.4) | 278 (42.1) | 8.1 | 26.9 | 14.9 |
| All | 12 580 (100) | 1864 (100) | 14.8 | 3394 (100) | 661 (100) | 5.3 | 19.5 | 35.5 |
AAO = age at onset; PDGT = Parkinson’s disease-relevant genetic test.