Table 6.
Comparison between perioperative outcomes of MILR in cirrhosis patients with and without PHT
| Entire unmatched cohort | 1:1 PSM (nearest neighbour) | 1:1 CEM | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| All (N = 2327) | Cirrhosis PHT (N = 626) | Cirrhosis NPHT (N = 1701) | P-value | Cirrhosis PHT (N = 450) | Cirrhosis NPHT (N = 450) | P-value | Cirrhosis PHT (N = 290) | Cirrhosis NPHT (N = 290) | P-value (paired) | |
| Open conversion, n (%) | 137 (5.9) | 49 (7.8) | 88 (5.2) | 0.021 | 38 (8.4) | 25 (5.6) | 0.118 | 25 (8.6) | 13 (4.5) | 0.067 |
| Median operating time (IQR), min | 190.00 [136.00, 252.00] | 180.00 [124.00, 245.00] | 195.00 [140.00, 255.00] | 0.010 | 180.00 [124.50, 250.00] | 185.00 [134.00, 240.00] | 0.872 | 180.00 [124.25, 240.00] | 180.00 [130.00, 243.00] | 0.563 |
| Median blood loss (IQR), ml | 150.00 [50.00, 300.00] | 200.00 [50.00, 350.00] | 110.00 [50.00, 300.00] | <0.001 | 200.00 [100.00, 400.00] | 120.00 [50.00, 300.00] | <0.001 | 200.00 [100.00, 327.50] | 150.00 [50.00, 300.00] | 0.046 |
| Blood loss > 500 mls, n (%) | 262 (11.7) | 89 (14.8) | 173 (10.6) | 0.008 | 70 (15.9) | 39 (9.0) | 0.003 | 36 (13.0) | 34 (12.5) | 0.787 |
| Intraoperative blood transfusion, n (%) | 198 (8.5) | 65 (10.4) | 133 (7.8) | 0.061 | 51 (11.3) | 31 (6.9) | 0.025 | 24 (8.3) | 17 (5.9) | 0.296 |
| Pringle maneuver applied, n (%) | 1033 (45.0) | 281 (45.4) | 752 (44.8) | 0.850 | 199 (44.5) | 186 (41.6) | 0.446 | 127 (43.9) | 113 (39.6) | 0.298 |
| Median postoperative stay, d (IQR), mean (SD) | 6.00 [4.00, 8.00], 7.09 (7.65) | 5.00 [4.00, 8.00], 7.08 (6.96) | 6.00 [4.00, 8.00], 7.09 (7.89) | 0.231 | 5.77 [4.00, 8.00], 7.01 (6.21) | 5.00 [4.00, 7.00], 6.98 (12.59) | 0.141 | 5.00 [4.00, 7.00], 7.04 (7.23) | 5.00 [4.00, 8.00], 6.82 (5.29) | 0.887 |
| Postoperative morbidity, n (%) | 402 (17.3) | 128 (20.5) | 274 (16.2) | 0.017 | 78 (17.4) | 73 (16.3) | 0.721 | 54 (18.6) | 42 (14.5) | 0.201 |
| Major morbidity (Clavien-Dindo grade> 2), n (%) | 98 (4.2) | 33 (5.3) | 65 (3.8) | 0.155 | 23 (5.1) | 15 (3.3) | 0.243 | 11 (3.8) | 10 (3.4) | 1.000 |
| Reoperation, n (%) | 12 (0.5) | 3 (0.5) | 9 (0.5) | 1.000 | 2 (0.4) | 2 (0.4) | 1.000 | 1 (0.3) | 1 (0.3) | 1.000 |
| 30-day readmission, n (%) | 50 (2.2) | 12 (1.9) | 38 (2.2) | 0.754 | 11 (2.4) | 14 (3.1) | 0.663 | 6 (2.1) | 8 (2.8) | 0.789 |
| 30-day mortality, n (%) | 9 (0.4) | 2 (0.3) | 7 (0.4) | 1.000 | 1 (0.2) | 2 (0.4) | 1.000 | 2 (0.7) | 1 (0.3) | 1.000 |
| In-hospital mortality, n (%) | 13 (0.6) | 2 (0.3) | 11 (0.6) | 0.533 | 1 (0.2) | 1 (0.2) | 1.000 | 2 (0.7) | 2 (0.7) | 1.000 |
| 90-day mortality, n (%) | 15 (0.6) | 2 (0.3) | 13 (0.8) | 0.380 | 1 (0.2) | 3 (0.7) | 0.617 | 2 (0.7) | 3 (1.0) | 1.000 |