Table 1.
Moderate Level of Risk by Comparator Algorithms | Sex | eGFR (ml/min/1.73 m2) | Relative Performance of PREVENT Algorithm |
||
---|---|---|---|---|---|
% With Concordant Moderate Risk | % Reclassified to Low Risk | % Reclassified to High Risk | |||
FRS | Male | 90 | 47 | 52 | 1 |
60 | 50 | 49 | 1 | ||
45 | 85 | 6 | 9 | ||
30 | 47 | 0 | 53 | ||
Female | 90 | 71 | 24 | 5 | |
60 | 74 | 19 | 7 | ||
45 | 64 | 0 | 36 | ||
30 | 13 | 0 | 87 | ||
PCE (White) | Male | 90 | 82 | 15 | 3 |
60 | 83 | 13 | 4 | ||
45 | 68 | 0 | 32 | ||
30 | 20 | 0 | 80 | ||
Female | 90 | 88 | 5 | 7 | |
60 | 84 | 4 | 12 | ||
45 | 41 | 0 | 59 | ||
30 | 6 | 0 | 94 | ||
PCE (Black) | Male | 90 | 62 | 34 | 4 |
60 | 64 | 32 | 4 | ||
45 | 71 | 5 | 24 | ||
30 | 31 | 0 | 69 | ||
Female | 90 | 72 | 23 | 5 | |
60 | 76 | 18 | 6 | ||
45 | 66 | 0 | 34 | ||
30 | 18 | 0 | 82 | ||
SCORE2 moderate risk region, age <50 y | Male | 90 | 18 | 82 | 0 |
60 | 20 | 80 | 0 | ||
45 | 70 | 26 | 4 | ||
30 | 55 | 1 | 44 | ||
Female | 90 | 34 | 66 | 0 | |
60 | 40 | 60 | 0 | ||
45 | 73 | 9 | 18 | ||
30 | 24 | 0 | 76 | ||
SCORE2 moderate risk region, age ≥50 y | Male | 90 | 74 | 26 | 0 |
60 | 77 | 23 | 0 | ||
45 | 85 | 1 | 14 | ||
30 | 34 | 0 | 66 | ||
Female | 90 | 85 | 14 | 1 | |
60 | 88 | 10 | 2 | ||
45 | 68 | 0 | 32 | ||
30 | 17 | 0 | 83 |
eGFR = estimated glomerular filtration rate; FRS = Framingham risk score; PCE = pooled cohort equation; PREVENT = Predicting Risk of cardiovascular disease EVENTs algorithm; SCORE2 = Systematic COronary Risk Evaluation2.