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. 2024 Jul 18;3(8):101122. doi: 10.1016/j.jacadv.2024.101122

Table 1.

Reclassification of Moderate Level of Risk as Determined by Comparator Algorithms

Moderate Level of Risk by Comparator Algorithms Sex eGFR (ml/min/1.73 m2) Relative Performance of PREVENT Algorithm
% With Concordant Moderate Risk % Reclassified to Low Risk % Reclassified to High Risk
FRS Male 90 47 52 1
60 50 49 1
45 85 6 9
30 47 0 53
Female 90 71 24 5
60 74 19 7
45 64 0 36
30 13 0 87
PCE (White) Male 90 82 15 3
60 83 13 4
45 68 0 32
30 20 0 80
Female 90 88 5 7
60 84 4 12
45 41 0 59
30 6 0 94
PCE (Black) Male 90 62 34 4
60 64 32 4
45 71 5 24
30 31 0 69
Female 90 72 23 5
60 76 18 6
45 66 0 34
30 18 0 82
SCORE2 moderate risk region, age <50 y Male 90 18 82 0
60 20 80 0
45 70 26 4
30 55 1 44
Female 90 34 66 0
60 40 60 0
45 73 9 18
30 24 0 76
SCORE2 moderate risk region, age ≥50 y Male 90 74 26 0
60 77 23 0
45 85 1 14
30 34 0 66
Female 90 85 14 1
60 88 10 2
45 68 0 32
30 17 0 83

eGFR = estimated glomerular filtration rate; FRS = Framingham risk score; PCE = pooled cohort equation; PREVENT = Predicting Risk of cardiovascular disease EVENTs algorithm; SCORE2 = Systematic COronary Risk Evaluation2.