Figure 7.

Aggregated cardiac activity at rest (during International Affective Picture System intertrial intervals) pre- and post-transcranial focused ultrasound (TFUS) targeting of the amygdala (yellow) vs. the entorhinal cortex (blue). Effects involving TFUS target (amygdala, entorhinal cortex) and pre/post (pre-TFUS, post-TFUS) on the average interbeat interval between International Affective Picture System trials. TFUS targeting the amygdala decreased interbeat intervals (i.e., increased heart rate) during intertrial intervals of the mildly aversive International Affective Picture System task. Increased intertrial intervals indicate a lower heart rate. The horizontal dashed line in the box plot indicates the mean. The horizontal solid line in the box plot indicates the median. Individual changes are plotted in Figure S4A.