Figure 4.

Isoform switching induced by pathogen stimulation

(A) Overlap of isoform switching genes between the four stimulus conditions.

(B) Pathway network analysis derived from genes found to undergo isoform switching (IS) upon pathogen stimulation. Each pathway is colored by p value, where a darker red indicates a lower p value.

(C) Proportions of total IS events in each stimulated condition per IS consequence.

(D) Number of IS by category of switch pairs. Categories are defined by involvement of novel transcripts in a given IS. “Novel down” indicates that the isoform switched from a higher proportion of the novel transcript in control to a higher proportion of a known transcript in the stimulus condition. “Both known” indicates that the IS occurs between 2 reference transcripts.

(E) Fraction of each transcript novelty combination per IS consequence. Normalized by total number of IS events per novelty category.

See also Figures S5–S8.