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. Author manuscript; available in PMC: 2024 Aug 1.
Published in final edited form as: Nat Protoc. 2023 Oct 11;18(12):3662–3689. doi: 10.1038/s41596-023-00891-y

Table 1:

Summary of stem cell-derived in vitro embryo models

Name Cell types used Aggregation conditions References
ETS embryo ESCs and TSCs Matrigel 9, 10
ETX embryo ESCs, TSCs and XEN cells AggreWell 11
ETiX embryo (or iETX embryo) ESCs, TSCs and iGata4 ESCs (induced XEN cells) AggreWell 7, 13
EiTiX embryo ESCs, iCdx2 ESCs (induced TSCs), iGata4 ESCs (induced XEN cells) AggreWell 8