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. 2024 Jul 8;16(30):5146–5153. doi: 10.1039/d4ay00560k

Range characterisation of the three dsRNA quantification methods evaluated (HPLC, dot blot and ELISA) in terms of limit of detection (LOD), limit of quantification (LOQ), decision limit (CCα) and the detection capability (CCβ).

Parameter Analytical method
HPLC Dot blot ELISA
(g L−1) σ (g L−1) (g L−1) σ (g L−1) (g L−1) σ (g L−1)
LOD 1.41 × 10−2 1.78 × 10−3 2.01 × 10−1 5.96 × 10−2 1.51 × 10−5 3.21 × 10−6
LOQ 4.27 × 10−2 5.40 × 10−3 6.09 × 10−1 1.81 × 10−1 4.56 × 10−5 9.73 × 10−6
CCα 9.95 × 10−3 1.26 × 10−3 1.42 × 10−1 4.21 × 10−2 1.06 × 10−5 2.27 × 10−6
CCβ 1.70 × 10−2 2.14 × 10−3 2.42 × 10−1 7.17 × 10−2 1.81 × 10−5 3.86 × 10−6