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. 2024 Jul 19;12:1407097. doi: 10.3389/fcell.2024.1407097

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Copyright © 2024 Machi, Altilio, Qi, Morales, Silvestre, Hernandez, Da Costa-Santos, Santana, Neghabi, Nategh, Castro, Werneck-de-Castro, Ranji, Evangelista, Vazquez-Padron, Bernal-Mizrachi and Rodrigues.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Transthoracic echocardiography analysis of control and endothelial c-Myc overexpression mice. Animals were analyzed after 18-weeks under control and western diet. (A) Myocardial performance index (MPI). (B) Isovolumetric contraction time (IVCT). (C) E/A ratio. (D) Left ventricular mass. Dots represent individual animals and filled circles represent the mean ± standard deviation. LV, Left ventricle; CT, Control; OE, Endothelial c-Myc overexpression; CTD, control diet (n = 3–4); WD, western diet (n = 3–4). *p < 0.05, **p < 0.01, ***p < 0.005.