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. 2024 Jul 19;15:1445170. doi: 10.3389/fphar.2024.1445170

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Copyright © 2024 Wang, Xie, Qian, Ding, Pang, Chen, Zhang and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Role of RAB42 knock-down in decreasing the cellular malignancy of LIHC. (A,B) Determining the knockdown efficiency of RAB42 in MHCC-97H and HepG2 cells by Western blotting. (C) The effect of RAB42 knockdown on cellular survival determined by CCK-8 assays. (D–F) The effect of RAB42 knockdown on cellular migratory potential determined by wound healing assays. Representative images are shown (D,E). (G,H) The effect of RAB42 knockdown on the cellular invasion potential determined by transwell assays. Representative images are shown (G). ns, not significant; *, p < 0.05; ***, p < 0.001; n = 3.