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Human plasma-like media (HPLM) attenuates leukemia cell sensitivity to thiopurine chemotherapeutics. 6-MP (A–E) and 6-TG (F–J) dose-response curves for leukemia cells (NALM-6, A, F; REH, B, G; SEM, C, H; Jurkat, D, I; CEM, E, J) in regular or HPLM media. Leukemia cell viability was assessed after 48 hours of drug treatment using the CellTiter-Glo Luminescent Cell Viability Assay. Error bars represent the mean ± SD of three technical replicates.
