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. 2024 Apr 23;25(4):751–772. doi: 10.1007/s11154-024-09882-0

Fig. 3.

Fig. 3

Mediation of progesterone and allopregnanolone cellular actions via their membrane, receptors in the cytoplasmic membrane, the nucleus and organelles [mitochondrion, endoplasmic reticulum (ER)] in the central nervous system. SRC proto-oncogene (SRC), non-receptor tyrosine kinase [previously named: v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog], progesterone receptor [(PR), the classic nuclear receptor], sigma-1 receptor (Sigma − 1R), membrane-associated protein progesterone receptor-membrane component 1 (PGRMC1), progesterone membrane receptor (mPR), γ-aminobutyric acid receptor A (GABA)A