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. 2024 Jun 4;143(7):907–919. doi: 10.1007/s00439-024-02674-1

Table 1.

TFs predicted to bind at the SNP sequences with p < 0.01

SNP Name P-value
(common allele)
P-value
(rare allele)
p-value
(combined)
rs10757278 V$STAT_01 0.0080 0.077 0.0052
rs7859727 V$GATA6_01 < 0.00057 0.824 0.0041

Calculated with the Transcription factor Affinity Prediction (TRAP) Web Tool TRAP (multiple sequences), using the matrix file ‘transfac_2010.1 vertebrates’, the background model ‘human_promoters’ and 10 bp +/- the SNP alleles:

rs10757278: CATTCCGGTA[A/G]GCAGCGATGC,

rs7859727: ATCTGAATGA[T/C]AGGCATTCCT