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. 2024 Apr 29;34(7):1376–1384. doi: 10.4014/jmb.2403.03008

Table 4.

Drug targets of viral protease and non-structural proteins.

Viral target Drugs or therapy methods
HIV Protease inhibitors Darunavir, Lopinavir, Ritonavir, etc.
SARS-CoV-2 Mpro inhibitors Ebselen, Tideglusib, Carmofur, α-ketoamides, Pelitinib, etc.
SARS-CoV-2 PLpro inhibitors VIR250, VIR251, GRL0617, etc.
HCV NS3/4A protease Grazoprevir, etc.
HCV NS1 inhibitors Epigallocatechine gallate, etc.