Table 1.
Missing data (N) | BLV (n=114) | BLV+Peg-IFN (n=69) | p value∗ | |
---|---|---|---|---|
Clinical characteristics | ||||
Age†, years | 42 [35–51] | 42 [36–51] | 0.8 | |
Female‡ | 37 (32) | 23 (33) | 0.9 | |
BMI†, kg/m2 | 26 | 25.1 [22.3–27.6] | 24.5 [22.5–28.2] | 0.8 |
HIV‡ | 2 | 21 (19) | 8 (12) | 0.2 |
Liver stiffness measurement (FibroScan®)†, kPa | 64 | 12 [9–19] | 11 [8–17] | 0.3 |
Cirrhosis‡ | 83 (73) | 52 (75) | 0.7 | |
Platelets†, per cm3 | 5 | 144 [83–196] | 163 [122–230] | 0.01 |
Co-medication with NUC‡ | 97 (85) | 51 (74) | 0.06 | |
Viral and biochemical characteristics | ||||
HBeAg-negative‡ | 35 | 74 (85) | 56 (92) | 0.2 |
HDV RNA† (log10 IU/ml) | 6.5 [5.3–6.9] | 6.7 [5.5–7.3] | 0.3 | |
Undetectable HBV DNA‡ | 15 | 88 (81) | 36 (60) | 0.03 |
HBsAg† (log10 IU/ml) | 111 | 3.7 [2.9–4.1] | 3.7 [3.4–4.1] | 0.5 |
ALT† (IU/L) | 3 | 78 [51.8–119] | 84 [54.5–143] | 0.5 |
Follow up†, days | 335 [273–358] | 341 [331–331] | 0.2 |
ALT, alanine transaminase; BLV, bulevirtide; NUC, nucleos(t)ide analogs; Peg-IFN, pegylated interferon.
Wilcoxon test; Pearson’s test.
Median [IQR].
n (%).