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. 2024 Jul 8;27(8):110475. doi: 10.1016/j.isci.2024.110475

Figure 3.

Figure 3

SARS-CoV-2 and innate immune response in proviral factor-knockout cells

(A–C) Quantification of IFNβ (A), CXCL10 (B), IL-6, and TNF-α (C) mRNA in TRIM28, TRIM33, EHMT1, or EHMT2 knockout cells at 24 h post-infection. Poly(I:C) (high molecular weight) was transfected as a positive control in control cells, and cells were harvested 24 h post-infection. For TNF-α, human reference cDNA (30 ng equiv. total RNA) was used as a positive control for qPCR detection. Data are presented as the mean ± SD of three independent experiments. N.D., not detected.