Table 8.
Inhibitory Acetylcholinesterase activities of C. esculentus extracts.
| Sample | Concentration (mg/mL) | Inhibition (%) | IC50 (mg/mL) ± SEM |
|---|---|---|---|
| Aqueous | 0.03125 | 6.32d ± 0.71 | 0.29 ± 0.27 |
| 0.0625 | 8.43d ± 1.38 | ||
| 0.125 | 12.11c ± 0.30 | ||
| 0.25 | 15.54b ± 2.13 | ||
| 0.5 | 19.41a ± 1.71 | ||
| 1.0 | 22.07a ± 0.62 | ||
| Butanol | 0.03125 | 16.55f ± 0.09 | 0.70 ± 0.10 |
| 0.0625 | 25.42e ± 0.17 | ||
| 0.125 | 37.65d ± 0.11 | ||
| 0.25 | 41.09c ± 0.43 | ||
| 0.5 | 50.41b ± 0.24 | ||
| 1.0 | 66.78a ± 1.42 | ||
| Dichloromethane | 0.03125 | 20.67f ± 0.22 | 0.80 ± 0.01 |
| 0.0625 | 31.90e ± 1.52 | ||
| 0.125 | 42.11d ± 0.74 | ||
| 0.25 | 47.60c ± 0.43 | ||
| 0.5 | 58.53b ± 1.30 | ||
| 1.0 | 73.03a ± 0.02 |
Values are the average of triplicates. ± = Standard deviation. Different alphabets indicate values that significantly differ (p < 0.05) from every treatment by Duncan's multiple range test. Butanol and dichloromethane as controls did not show any anti-cholinesterase activity.