. 2024 Jul 4;8:100118. doi: 10.1016/j.sleepx.2024.100118

Table 3.

Demographic, tremor characterization, risk factors and prodromic markers for PDD: comparison between ET-PPD and ET-nonPPD.

	ET-PDD (n = 4)	ET-nonPDD (n = 60)	p
Age (yrs)	75.75 (3.5)	72.98 (1.2)	0.640
Sex (m)	3 (75.0)	31 (53.4)	0.620
MoCA	18.25 (1.9)	20.91 (0.8)	0.187
Tremor characterization
Age of tremor onset (yrs)	65.25 (3.0)	57.67 (2.2)	0.526
Tremor duration (yrs)	10.50 (2.5)	15.12 (1.7)	0.663
ET-Plus	1 (25.0)	18 (30.0)	1.000
TETRAS ADL	18.75 (2.0)	15.52 (0.9)	0.249
TETRAS Performance	19.13 (2.2)	18.61 (0.9)	0.879
TETRAS total score	37.88 (2.4)	34.22 (1.6)	0.381
Activation conditions			0.884
kinetic	0	3(5.0)
postural	1 (25.0)	12(20)
both	3 (75.0)	45 (75.0)
Symmetry (assymmetric)	1 (25.0)	42 (70.0)	0.099
Tremor in locations other than hands	2 (50.0)	36 (60.0)	0.539
Rest tremor component	1 (25.0)	20 (33.3)	0.602
PPD Risk factors
Male gender	3 (75.0)	32 (53.3)	0.620
Pesticide exposure	0	5 (8.3)	0.716
Solvent exposure	1 (25.0)	10 (16.7)	0.539
Low caffeine exposure	1 (25.0)	15 (25.5)	1.000
Smocking
Actual	0	6 (10.0)	0.668
Never	1 (25.0)	19 (31.7)	0.631
Past only	2 (50.0)	25 (41.7)	0.566
Sibling with DP before 50	0	0
Other first degree relative	0	2 (3.3)	0.878
Prodromal markers
RBD – PSG	3 in 3^a)	2 in 9^a)	0.045
RBD – Questionnaire	3 (75.0)	8 (13.3)	0.014
DaT-Scan	4 (100.0)^b	1 in 7 (12.5)^b	0.010
UPDRS III >3	2 (50.0)	20 (33.3)	0.426
Constipation (UMSARS >1)	2 (50.0)	10 (16.7)	0.157
Erectile dysfunction (UMSARS >2)	2 in 3 (66.7)^c)	6 in 32 (18.8)^c)	0.124
Orthostatic hypotension	0	3 (5.0)	0.821
Excessive daytime sleepiness (ESS >9)	0	10 (16.7)	0.498
Depression (BDI>13)	1 (25.0)	6 (10.0)	0.378

^a)

Only patients with positive questionnaire were eligible for PSG study.

^b)

DaT-Scan was performed only if clinically indicated.

^c)

These percentages refer to a total population of 35 male patients.