TABLE 6.
Intestinal morphologic changes in individual calves following single or dual inoculation with group A and C bovine rotaviruses
| Virus inoculuma | PIDEb | Lymphoid hyperplasiac
|
Villous atrophyc
|
|||
|---|---|---|---|---|---|---|
| Mesenteric lymph nodes | Small intestined | Duodenum | Jejunum | Ileum | ||
| IND/A | 3 | + | ++ | + | + | + |
| NCDV/A | 4 | + | +/− | − | + | +/− |
| WD534tc/C | 4 | − | +/− | − | +/− | − |
| WD534tc/C + IND/A | 2 or 4 | + | ++ | ++ | ++ | ++ |
| WD534tc/C + NCDV/A | 4 | + | + | + | + | + |
a
Calves were inoculated at 6 to 8 days of age.
b
PIDE, postinoculation day of euthanasia.
c
Degree of histologic change (lymphoid hyperplasia and villous atrophy) from age-matched control: −, none (same as control); +/−, minimal, focal; +, mild, scattered; ++, moderate, widespread.
d
Small intestinal lamina propria, submucosa, and Peyer’s patch lymphoid tissues evaluated.