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. 2024 Aug 2;13:RP95257. doi: 10.7554/eLife.95257

Table 7. A summary of peak heights and HHPs obtained from the histograms in Figure 8.

Single and double Gaussian fitting methods were applied to the data. The significant difference between the peaks in the Gaussian fitting was statistically evaluated and indicated using an F-test. ‘ND’ indicates cases where the information was not determined.

Peak Height (nm) Half Helical Pitch (nm) Frequency
Peak 1(proportion)[F-test, p] Peak 2(proportion)[F-test, p] Peak 1(proportion)[F-test, p] Peak 2(proportion)[F-test, p]
(A) 2000 nM cofilin, 0.5 mM ATP/ on DPPC/DPTAP (75/25 wt%) 8.2±0.8
(100%)
ND 34.3±2.6
(100%)
ND Height: 1930
HHP: 1556
(B) 300 nM cofilin, 0.5 mM ATP/ on DPPC/DPTAP (90/10 wt%) 9.2±0.4
(47.0%)
[0.0204]
10.5±0.7
(53.0%)
[0.0204]
28.5±3.0
(55.1%)
[0.0135]
37.4±3.6
(44.9%)
[0.0135]
Height: 2212
HHP: 1780
(C) 300 nM cofilin, 1 mM ADP/ on DPPC/DPTAP (90/10 wt%) 8.4±0.5
(54.8%)
[0.0081]
9.9±0.7
(45.2%)
[0.0081]
30.1±3.8
(70.3%)
[0.0195]
37.8±2.9
(29.7%)
[0.0195]
Height: 3183
HHP: 2779
(D) 75 nM cofilin, 1 mM ATP, 10 mM Pi/ on DPPC/DPTAP (90/10 wt%) 8.3±0.7
(55.3%)
[1.48x10–6]
11.0±1.0
(44.7%)
[1.48x10–6]
30.3±2.9
(25.2%)
[0.0002]
38.7±3.6
(74.8%)
[0.0002]
Height: 2316
HHP: 1865