Fig. 2.

BLOSUM62 CLANS cluster map of conotoxin gene superfamilies generated using conotoxin precursor sequences. Colored circles represent individual precursor sequences, with edges connecting the circles corresponds to psi-blast P-values >1e−12. The superfamilies are circled by dashed lines except for clusters with 2 or fewer sequences. Individual conotoxins are color-coded according to the prey preference of the species they were identified from (orange: piscivorous species; green: molluscivorous species; and blue: vermivorous species).