Table 1.
Baseline demographic and clinical characteristics of patients undergoing open hernia repair by type of suture
| Type of suture | SMD | P-value | ||
|---|---|---|---|---|
| Barbed TCS | Conventional PDS suture | |||
| n = 446 | n = 375 | |||
| Age at index | ||||
| Median [IQR] | 61.8 [52.3; 68.9] | 61.3 [51.3; 69.0] | 0.0739 | 0.3995 |
| Age groups at index, n (%) | ||||
| < 50 years | 92 (20.6%) | 89 (23.7%) | 0.0726 | 0.5633 |
| 50–64 years | 181 (40.6%) | 147 (39.2%) | ||
| ≥ 65 years | 173 (38.8%) | 139 (37.1%) | ||
| Sex, n (%) | ||||
| Male | 222 (49.8%) | 196 (52.3%) | 0.0498 | 0.477 |
| Female | 224 (50.2%) | 179 (47.7%) | ||
| BMI | ||||
| Median [IQR] | 27.4 [24.6; 31.2] | 27.7 [24.5; 31.6] | 0.007 | 0.8266 |
| BMI categories, n (%) | ||||
| Underweight (< 18.5 kg/m2) | 5 (1.1%) | 3 (0.8%) | 0.1318 | 0.2263a |
| Normal (18 to < 25 kg/m2) | 121 (27.1%) | 105 (28.0%) | ||
| Overweight (25 to < 30 kg/m2) | 187 (41.9%) | 134 (35.7%) | ||
| Obese (≥ 30 kg/m2) | 133 (29.8%) | 133 (35.5%) | ||
| Any hernia repair 5 years prior to the index procedure, n (%) | ||||
| Yes | 6 (1.3%) | 9 (2.4%) | − 0.0779 | 0.261 |
| No | 440 (98.7%) | 366 (97.6%) | ||
| Any surgeries 5 years prior to the index procedure, n (%) | ||||
| Yes | 217 (51.3%) | 268 (71.5%) | − 0.4234 | < 0.0001 |
| No | 206 (48.7%) | 107 (28.5%) | ||
| Number of comorbidities | ||||
| Median [IQR] | 1.0 [0.0; 2.0] | 1.0 [0.0; 2.0] | 0.2349 | 0.0012 |
| Number of comorbidities, n (%) | ||||
| 0 | 128 (28.7%) | 132 (35.2%) | 0.2404 | 0.0151 |
| 1 | 118 (26.5%) | 117 (31.2%) | ||
| 2 | 94 (21.1%) | 68 (18.1%) | ||
| 3 | 61 (13.7%) | 32 (8.5%) | ||
| 4 + | 45 (10.1%) | 26 (6.9%) | ||
| Medication use at the time of the index procedure, n (%) | ||||
| Anticoagulation medicine | 112 (25.1%) | 25 (6.7%) | 0.5214 | < 0.0001 |
| Cortisone | 10 (2.2%) | 30 (8.0%) | − 0.2635 | 0.0001 |
| Immunosuppressive drugs | 37 (8.3%) | 28 (7.5%) | 0.0308 | 0.6611 |
| Use of mesh reinforcement, n (%) | ||||
| Yes | 403 (90.4%) | 355 (94.7%) | − 0.16423 | 0.0209 |
| Mesh repair method, n (%) | n = 403b | n = 355b | ||
| Onlay | 17 (4.2%) | 4 (1.1%) | 0.22042 | 0.0115 |
| Sublay | 363 (90.1%) | 320 (90.1%) | ||
| IPOM | 23 (5.7%) | 31 (8.7%) | ||
| Hernia defect size (cm2) | ||||
| Median [IQR] | 36.0 [15.0; 100.0] | 46.5 [16.0; 108.0] | − 0.0865 | 0.0378 |
SMD standardized mean difference, SD standard deviation, IQR interquartile range, BMI body mass index
a Fisher’s exact test was used instead of Chi-square test
b Denominator is the number of patients that used mesh reinforcement