Table. Changes in Semaglutide Prescriptions Filled by Drug Brand and Method of Payment Between January 2021 and December 2023a.
| Characteristic | Fills by method of payment | |||||||
|---|---|---|---|---|---|---|---|---|
| No. of monthly fills, mean (SD) | Proportion of monthly fills, mean (IQR) | |||||||
| 2021 | 2022 | 2023 | P valueb | 2021 | 2022 | 2023 | P valueb | |
| All semaglutide fills | 659 492 (147 800) | 1 148 123 (161 532) | 2 270 564 (326 866) | <.001 | NA | NA | NA | NA |
| Ozempic | ||||||||
| Total | 526 289 (95 463) | 909 927 (154 356) | 1 676 258 (246 594) | <.001 | NA | NA | NA | NA |
| Commercial | 346 850 (66 124) | 598 503 (104 237) | 1 027 892 (143 899) | <.001 | 65.8 (65.2-66.3) | 65.7 (65.2-66.2) | 61.4 (60.7-62.2) | <.001 |
| Medicaid | 40 096 (6371) | 75 385 (15 834) | 163 142 (26 309) | <.001 | 7.6 (7.5-7.9) | 8.2 (7.9-8.6) | 9.7 (9.5-10.0) | <.001 |
| Medicare Part D | 138 327 (22 854) | 233 028 (33 529) | 478 492 (78 055) | <.001 | 26.4 (26.0-26.7) | 25.7 (25.2-26.4) | 28.5 (27.8-29.3) | <.001 |
| Cash | 1017 (195) | 3011 (1255) | 6732 (292) | <.001 | 0.2 (0.2-0.2) | 0.3 (0.2-0.4) | 0.4 (0.4-0.4) | <.001 |
| Wegovy | ||||||||
| Total | 49 599 (30 209) | 70 958 (17 777) | 368 686 (94 174) | <.001 | NA | NA | NA | NA |
| Commercial | 43 501 (27 411) | 65 761 (16 149) | 329 340 (82 461) | <.001 | 86.0 (83.8-89.4) | 92.8 (92.4-93.4) | 89.5 (89.1-89.7) | .03 |
| Medicaid | 363 (351) | 2483 (649) | 30 797 (9721) | <.001 | 0.6 (0.3-0.9) | 3.6 (3.4-4.2) | 8.2 (8.2-8.5) | <.001 |
| Medicare Part D | 324 (187) | 700 (151) | 4438 (1785) | <.001 | 0.8 (0.6-0.7) | 1.0 (0.9-1.1) | 1.2 (0.9-1.5) | .02 |
| Cash | 5410 (2583) | 2014 (1593) | 4112 (689) | .24 | 12.7 (9.0-15.2) | 2.6 (1.6-3.1) | 1.2 (1.0-1.2) | <.001 |
| Rybelsus | ||||||||
| Total | 104 270 (20 656) | 167 238 (21 206) | 225 620 (10 501) | <.001 | NA | NA | NA | NA |
| Commercial | 73 242 (12 415) | 106 716 (12 283) | 130 991 (5390) | <.001 | 70.7 (68.7-72.2) | 63.9 (63.1-64.5) | 58.1 (57.6-58.4) | <.001 |
| Medicaid | 4696 (1557) | 12 544 (2856) | 19 687 (835) | <.001 | 4.4 (3.9-5.0) | 7.4 (6.9-8.1) | 8.7 (8.6-9.0) | <.001 |
| Medicare Part D | 25 952 (6926) | 47 715 (6103) | 74 311 (4683) | <.001 | 24.5 (23.4-26.2) | 28.5 (28.3-28.7) | 32.9 (32.4-33.6) | <.001 |
| Cash | 380 (226) | 263 (42) | 631 (220) | .01 | 0.4 (0.2-0.6) | 0.2 (0.1-0.2) | 0.3 (0.2-0.3) | .20 |
Abbreviation: NA, not applicable.
a
These data are from IQVIA’s National Prescription Audit PayerTrak on monthly prescription fills dispensed at retail pharmacies in the US.
b
P values represent the level of significance using a t test for the difference between 2023 and 2021.