| Methods |
Randomised trial. No mention of method of randomisation. Not placebo‐controlled or blinded. |
| Participants |
82 women treatment 43 control 39. Inclusions: 20‐34 weeks' pregnant. PPROM confirmed by sterile speculum. Singleton pregnancy only. |
| Interventions |
Treatment group: ampicillin 1 g IV every 6 hours for 24 hours. Maintained on oral 500 mg ampicillin 6‐hourly until delivery. In labour they were recommenced on 1 g IV ampicillin. |
| Outcomes |
Death only included. |
| Notes |
|
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Random sequence generation (selection bias) |
Unclear risk |
No information given. |
| Allocation concealment (selection bias) |
Unclear risk |
No information given. |
| Blinding (performance bias and detection bias)
All outcomes |
High risk |
Not blinded. |
| Incomplete outcome data (attrition bias)
All outcomes |
Low risk |
Data appear complete. |
| Selective reporting (reporting bias) |
Unclear risk |
Protocol not available. |
| Other bias |
Unclear risk |
No information available. |
