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. 2024 Aug 3;16:41. doi: 10.1186/s13099-024-00635-7

Fig. 2.

Fig. 2

The mechanism by which Am increases intestinal integrity. (A): Am upregulates the expression of the NLRP6 inflammasome, which accelerates autophagy in goblet cells and reduces endoplasmic reticulum stress, thereby promoting mucus secretion. (B): Am increases the expression of the Wnt signaling pathway and promotes the production of SCFAs, which interact with GPCR41/43 to maintain the proliferation of ISCs and promote the differentiation of Paneth cells and goblet cells