Table 2.

Termination criteria for DigIn2Perio

Practices	Patients	Study
- Revocation of the consent to participate - Permanent loss of the infrastructure required to perform the study - Permanent closing - Relocation to a state outside of Baden-Württemberg or North Rhine-Westphalia - Transfer to an owner who is not willing to participate or who fulfills at least one exclusion criterion - Permanent loss of responsible assistant if no other person is willing/able to continue	- Revocation of the consent to participate - Death - Occurrence of at least one exclusion criterion in the course of the study - Permanent change of practice	- Permanent loss of the study funding - Loss of and/or actual incapacity to act at the study administration - Loss of project partners whose contributions are indispensable for the study, unless these contributions can be acquired elsewhere - Changes in legal regulations or the security situation that make it impossible to continue