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. 2024 Aug 3;10:144. doi: 10.1038/s41531-024-00761-8

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — A The Venn diagram and the network graph show 13 LRRK2 interactors presenting the same differential expression pattern in the LRRK2-PD and the sPD cohorts in comparison with controls. In the network graph, interactors with significant differential expression profiles are colour-coded based on up-regulation (red) and down-regulation (blue). B The bubble graph shows the GO-BP terms enriched for the 13 LRRK2 interactors that presented similar alterations in the 2 PD conditions as compared to controls.