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. 2024 Aug 3;14:17999. doi: 10.1038/s41598-024-68835-4

Table 1.

Baseline clinical characteristics and univariate analysis of the variables and AVF.

Variables All patients (n = 674) AVF group (n = 58) non-AVF group (n = 616) P Value
Age, years 70.20 ± 8.23 73.74 ± 7.94 69.87 ± 8.18 0.001*
BMI, kg/m2 22.99 ± 2.97 21.48 ± 2.71 23.13 ± 2.96  < 0.001*
History of hypertension, n (%) 230 (34.1) 19 (32.8) 211 (34.3) 0.818
History of diabetes, n (%) 132 (19.6) 9 (15.5) 123 (20.0) 0.414
Tobacco use, n (%) 52 (7.7) 8 (13.8) 44 (7.1) 0.119
Alcohol use, n (%) 6 (0.9) 1 (1.7) 5 (0.8) 1.000
Steroid medication, n (%) 23 (3.4) 4 (6.9) 19 (3.1) 0.250
Bisphosphonate therapy, n (%) 263 (39.0) 22 (37.9) 241 (39.1) 0.859
Previous history of OVCF, n (%) 115 (17.1) 20 (34.5) 95 (15.4)  < 0.001*
Duration of follow-up, mon 18.85 ± 3.43 19.38 ± 3.42 18.80 ± 3.43 0.219
Fracture location, n (%) 0.569
 TL junction 445 (66.0) 35 (60.4) 410 (66.6)
 Non-TL junction 139 (20.6) 13 (22.4) 126 (20.4)
 Non-TL + TL junction 90 (13.4) 10 (17.2) 80 (13.0)
The number of fractured vertebrae, n (%) 0.177
 1 509 (75.5) 38 (65.5) 471 (76.5)
 2 118 (17.5) 14 (24.1) 104 (16.9)
 ≥ 3 47 (7.0) 6 (10.4) 41 (6.6)
Operative method, n (%) 0.540
 PVP 488 (72.4) 40 (69.0) 448 (72.7)
 PKP 186 (27.6) 18 (31.0) 168 (27.3)
Cement volume, ml 4.37 ± 1.01 4.22 ± 0.80 4.38 ± 1.03 0.251
Cement distribution pattern, n (%) 0.481
 Trabecular type 469 (69.6) 38 (65.5) 431 (70.0)
 Compact type 205 (30.4) 20 (34.5) 185 (30.0)
Cement leakage, n (%) 129 (19.1) 13 (22.4) 116 (18.8) 0.507
Intradiscal cement leakage, n (%) 86 (12.8) 11 (19.0) 75 (12.2) 0.138
HU value 68.67 ± 28.36 49.86 ± 22.22 70.44 ± 28.25  < 0.001*

SVF subsequent vertebral fracture, BMI body mass index, TL thoracolumbar, PVP percutaneous vertebroplasty, PKP percutaneous kyphoplasty, HU Hounsfield unit.

*P < 0.05 was considered statistically significant.