Table 1.
Hematological and biochemical analyses of peripheral blood from BALB/c mice (n = 4 biologically independent mice/group)
| Parameters | Dose 1 | Dose 2 | Control |
|---|---|---|---|
| Hematological | |||
| Red blood cells (x106/μL) | 10.1 ± 0.0 | 9.9 ± 1.0 | 10.1 ± 0.1 |
| Hemoglobin (g/dL) | 15.2 ± 0.0 | 15.0 ± 1.4 | 15.5 ± 0.5 |
| MCV (fL) | 47.0 ± 0.2 | 45.5 ± 0.5 | 47.5 ± 0.5 |
| Hematocrit (%) | 47.0 ± 0.2 | 46.0 ± 5.0 | 48.0 ± 1.0 |
| Reticulocytes (%) | 3.4 ± 0.1 | 2.1 ± 0.0 | 2.2 ± 0.3 |
| MCH (pg) | 15.0 ± 0.0 | 15.0 ± 0.0 | 15.5 ± 0.5 |
| Leukocytes (x103/μL) | 3.1 ± 0.0 | 3.1 ± 2.0 | 4.8 ± 0.9 |
| Lymphocytes (%) | 72.0 ± 0.3 | 67.0 ± 2.0 | 78.0 ± 2.0 |
| Neutrophils (%) | 20.0 ± 0.1 | 25.0 ± 1.0 | 16.0 ± 2.0 |
| Monocytes (%) | 2.0 ± 0.0 | 3.0 ± 1.0 | 1.5 ± 0.5 |
| Eosinophils (%) | 3.0 ± 0.0 | 3.4 ± 0.5 | 2.5 ± 0.5 |
| Basophils (%) | 0.0 ± 0.0 | 0.5 ± 0.0 | 0.5 ± 0.0 |
| Biochemical | |||
| Creatinine (mg/L) | 4.0 ± 0.0 | 4.0 ± 0.8 | 4.2 ± 0.4 |
| BUN (mg/dL) | 23.0 ± 5.7 | 20.6 ± 6.6 | 27.0 ± 2.2 |
| Urea (g/L) | 0.5 ± 0.1 | 0.4 ± 0.1 | 0.5 ± 0.0 |
| ALT (x103 UI/L) | 2.8 ± 1.5 | 2.6 ± 0.4 | 2.1 ± 0.4 |
| AST (x103UI/L) | 2.5 ± 0.6 | 4.0 ± 0.6 | 3.4 ± 0.3 |