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. 2024 Jul 22;12:1439883. doi: 10.3389/fbioe.2024.1439883

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Copyright © 2024 Zhou, Gao, Yao, Lu, Dong, Wang, Zhang, Sun, Li and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Biocompatibility test results of SCP NPs. (A) The hemolytic test of SCP NPs and its main components (n = 3); (B) The survival rate of mice in each group in the acute toxicity test; (C) The average body weight change curve of mice in each group in the acute toxicity test; (D) The concentrations of inflammatory factors TNF-α and IL-6 in mice blood in each group during the first and second weeks of acute toxicity test (n = 3); (E) The HE staining results of the main organ tissues of mice in each group during the first week of acute toxicity test; (F) The main blood biochemical indicators of mice in each group in the first and second weeks of acute toxicity test (n = 3).