Table 2.
Main multimodal imaging features and etiology of five types of OVAs.
| OVA types | Carotid/intracranial arterial DSA | Multimodal imaging features | Etiology | ||
|---|---|---|---|---|---|
| Slit-lamp photo | Color fundus photo | Imaging features of OA on CTA | |||
| 1 | No visualization of the proximal trunk OA | Mydriasis | Pale optic disc/retina/choroid, retinal intra-arterial emboli, punctate hemorrhage on the retinal surface | No visualization of the proximal trunk OA | Autologous fat induced OAO |
| 2 | Poor visualization of the distal trunk OA and most distal branches | Uveitis, iris atrophy, pigmentation on the lens surface, mydriasis | Pale optic disc/retina/choroid, retinal intra-arterial emboli, triangular choroidal non-perfused areas | Poor or no visualization of the distal trunk OA | HA-induced incomplete OAO |
| 3 | No visualization of the distal trunk OA | Conjunctival congestion, cornea edema, hyphema, uveitis, iris neovascularization | Optic atrophy, extensive retinal artery occlusion | No visualization of the distal trunk OA | HA-induced or atherosclerotic occlusion of distal OA |
| 4 | Reversed visualization of blood flow in the trunk OA | Mydriasis, hyphema, iris neovascularization | Optic disc neovascularization, retinal artery occlusion and cotton wool spots, pale optic disc/retina, vitreous hemorrhage | Poor visualization of the distal trunk OA | Ipsilateral internal carotid artery occlusion or severe stenosisa |
| 5 | Visualization of the narrowed trunk OA | Mydriasis | Swollen and hemorrhagic optic disc, RAO with pallor edema in the corresponding blood supply retina, Optic disc neovascularization, vitreous hemorrhage | Poor or no visualization of the distal trunk OA | Variety degrees of stenosis of the ipsilateral ICA or OA |
CTA, computed tomographic angiography; DSA, digital subtraction angiography; HA, hyaluronic acid; ICA, internal carotid artery; OA, ophthalmic artery; OAO, ophthalmic artery occlusion; OVA, ocular vascular accident; RAO, retinal artery occlusion.
Severe stenosis of ipsilateral ICA indicates 70–99% stenosis of ipsilateral ICA.