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Comparison of primate RRE sequences. Secondary structures of the experimentally determined (HTLV-1 [HTLV-I] and HTLV-2 [HTLV-II]) or predicted (STLV and HTDV/HERV-K) Rex or cORF binding sites (relevant nucleotides are underlined) were compared by using the algorithm contained in the DNASIS software (Hitachi). Similar to the RxRE binding sites, the putative HTDV/HERV-K binding site is located on a stem-loop structure displaying a characteristic bulge.
