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In vitro activity (IC50) against Toxoplasma gondii, cytotoxicity (CC50) on human Hs27 cells of (S a)-2ab (R a)-2ab, rac-2ab, and pyrimethamine (PYR) Values shown in the table represent the means of three independent experiments each done in duplicate (n = 6) ± S.D.
| Compound | IC50 (µM) | CC50 (µM) |
|---|---|---|
| (S a)-2ab | 0.31 ± 0.03 | >200 |
| (R a)-2ab | 0.10 ± 0.01 | >200 |
| rac-2ab | 0.11 ± 0.02 | >200 |
| PYR | 0.22 ± 0.05 | >100 |
