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. 2024 Jul 22;14:1427740. doi: 10.3389/fonc.2024.1427740

Table 2.

Cox proportional hazard model to detect the effect of the four variables; the overall model was significant (Chi-Quadrat = 38.17; p< 0.001).

Regression coefficient
(95% CI)
Hazard ratio, HR,
(95% CI)
Z- score P-value
CRP level ≥ 5.5 mg/l 1.28
(0.49–2.06)
3.58
(1.64–7.83)
3.2 0.001
NSE level
≥ 22.8 µg/l
1.28
(0.5–2.06)
3.6
(1.66–7.83)
2.4 0.001
MELD-Score ≥11 1.38
(0.62–2.13)
3.97
(1.87–8.45)
3.58 < 0.001
Age ≥ 75 years 1.0
(0.18–1.83)
3.73
(1.2–6.21)
2.7 0.017

CRP, c-reactive protein; NSE, neuron-specific enolase; MELD, model of end stage liver disease; CI, confidence interval.