Table 2.

Association of Lp(a) and oxidized phospholipids with extracoronary vascular disease

Biomarkers	Univariable Model			Multivariable Model
	OR (95% CI)	P Value	C-Statistic	OR (95% CI)	P Value	C-Statistic
Lp(a)
Log(2), per 1 unit increment	1.16 (1.00, 1.35)	0.04	0.55	1.15 (0.97, 1.36)	0.11	0.82
Level ≥150 nmol/L	1.96 (1.14, 3.36)	0.01	0.54	2.14 (1.03, 4.44)	0.04	0.82
OxPL-apoB
Log(2), per 1 unit increment	1.36 (1.02, 1.81)	0.03	0.54	1.18 (0.83, 1.70)	0.36	0.81
Level ≥8.2 nmol/L	1.75 (1.12, 2.73)	0.01	0.55	1.24 (0.69, 2.17)	0.46	0.81
OxPL-apo(a)
Log(2), per 1 unit increment	1.11 (0.94, 1.33)	0.23	0.54	1.04 (0.84, 1.30)	0.72	0.81
Level ≥ 35.8 nmol/L	1.84 (1.18, 2.88)	0.007	0.56	1.64 (0.92, 2.92)	0.09	0.82
Combination of levels
Lp(a)&OxPL-apoB	2.17 (1.25, 3.76)	0.006	0.55	2.35 (1.13, 4.91)	0.02	0.82
Lp(a)&OxPL-apo(a)	1.96 (1.14, 3.36)	0.01	0.54	2.14 (1.03, 4.44)	0.04	0.82
OxPL-apoB&OxPL-apo(a)	2.11 (1.33, 3.36)	0.002	0.57	1.74 (0.96, 3.18)	0.07	0.82
Lp(a)&OxPL-apoB&OxPL-apo(a)	2.17 (1.25, 3.76)	0.006	0.55	2.35 (1.12, 4.91)	0.02	0.82

Multivariable model: age, sex, race, systolic blood pressure, HDL-C, total cholesterol, diabetes, smoking and history of cardiovascular disease. apoB, apolipoprotein B; apo(a), apolipoprotein(a); CI, confidence interval; Lp(a), lipoprotein(a); OR, odds ratio; OxPL, oxidized phospholipids.