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. 2024 Jul 22;15:1413250. doi: 10.3389/fmicb.2024.1413250

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Copyright © 2024 Shaikh, Faiyazuddin, Khan, Pathan, Syed, Gholap, Akhtar, Sah, Mehta, Sah, Bonilla-Aldana, Luna and Rodriguez-Morales.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The chikungunya virus replication cycle includes (1) virus binding to a specific receptor in the membrane, (2) clathrin-mediated endocytosis, (3) membrane fusion, (4) capsid disassembly, (5) translation, (6) processing, (7) replication, (8) 26’s subgenomic RNA translation, (9) autoproteolysis, (10) cleavage in the endoplastic reticulum and initial folding, and (11). Glycosylation and structural conformation, (12) migration to the plasma membrane, (13) nucleocapsid assembly, and (14) the release of new viruses (Created by using Biorender.com).