Table V:
Clinical outcomes among men with diagnosed HIV infection who have sex with men, stratified by amphetamine use in the past 12 months, Medical Monitoring Project, 2015–2016
| Amphetamine usea | No amphetamine use | Bivariate analysis | p-value | ||||
|---|---|---|---|---|---|---|---|
| Weighted Column % | 95% CI | Weighted Column % | 95% CI | PR | 95% CI | ||
| Engaged in care b,c | |||||||
| Yes | 72.7 | 66.3, 79.1 | 80.5 | 78.6, 82.5 | 0.90 | 0.82, 0.99 | 0.0135 |
| No | 27.3 | 20.9, 33.7 | 19.5 | 17.5, 21.4 | --- | ||
| Currently taking ART b | |||||||
| Yes | 86.7 | 81.3, 92.0 | 93.6 | 92.3, 95.0 | 0.93 | 0.87, 0.99 | 0.0013 |
| No | 13.3 | 8.0, 18.7 | 6.8 | 5.5, 8.1 | --- | ||
| Perfect adherence score d | |||||||
| Yes | 22.0 | 17.0, 26.9 | 46.7 | 44.4, 48.9 | 0.47 | 0.38, 0.59 | <0.0001 |
| No | 78.0 | 73.1, 83.0 | 53.3 | 51.1, 55.6 | --- | ||
| Geometric mean CD4 count ≥ 350 b | |||||||
| Yes | 81.3 | 75.8, 86.9 | 82.4 | 80.7, 84.0 | 0.99 | 0.92, 1.06 | 0.7124 |
| No | 18.7 | 13.1, 24.2 | 17.6 | 16.0, 19.3 | --- | ||
| Durable viral suppression b,e | |||||||
| Yes | 53.9 | 47.3, 60.5 | 66.9 | 64.5, 69.3 | 0.81 | 0.71, 0.91 | 0.0001 |
| No | 46.1 | 39.5, 52.7 | 33.1 | 30.7, 35.5 | --- | ||
| Major or other depression f | |||||||
| Yes | 33.0 | 27.1, 38.8 | 19.2 | 17.4, 21.0 | 1.72 | 1.41, 2.08 | <0.0001 |
| No | 67.0 | 61.2, 72.9 | 80.8 | 79.0, 82.6 | --- | ||
Note: All variables measured by self-report within the past 12 months before interview except where noted. Abbreviations: HIV = human immunodeficiency virus; PR = prevalence ratio; CI = confidence interval; ART = antiretroviral therapy
Includes methamphetamine and/or other amphetamine use in the past 12 months
Measured through medical record abstraction
Defined as having received at least two elements of outpatient HIV care at least 90 days apart; outpatient HIV care was defined as any of the following: encounter with an HIV care provider (could also be self-reported), viral load test result, CD4 test result, HIV resistance test or tropism assay, ART prescription, PCP prophylaxis, or MAC prophylaxis
Composite score, with range from 0 to 100 (higher score indicates better adherence), based on adherence on 3 domains (number of days of missed doses per month, frequency of taking medication, and a self-rated adherence scale); a perfect score was defined as equal to 100
All viral loads over the past 12 months <200 copies/mL
Based on responses to the Patient Health Questionnaire (PHQ-8) and criteria from the Diagnostic and Statistical Manual of Mental Disorders, fourth edition (DSM-IV)