Figure 5.
Aging aggravated decreases and hindered recovery of lipid metabolism gene expression in AEC2s after bleomycin injury. (A) IPA pathway analysis of mouse AEC2s from Day 4 bleomycin-injured lungs, old versus young from dataset GSE157995. (B) Violin plots of expression of fatty acid biosynthesis– and metabolism-related genes in AEC2s grouped by age and days after injury (red, young; blue, old). (C) Violin plots of expression of phosphatidylcholine biosynthesis–related genes of AEC2s grouped by age and days after injury (red, young; blue, old). IPA = ingenuity pathway analysis.